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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
ACTR3
All Species:
47.58
Human Site:
S354
Identified Species:
69.78
UniProt:
P61158
Number Species:
15
Phosphosite Substitution
Charge Score:
-0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P61158
NP_005712.1
418
47371
S354
L
K
L
S
E
E
L
S
G
G
R
L
K
P
K
Chimpanzee
Pan troglodytes
XP_001143822
413
46798
L349
V
V
D
A
R
L
R
L
S
E
E
L
S
G
G
Rhesus Macaque
Macaca mulatta
Dog
Lupus familis
XP_853309
565
63553
S501
L
K
L
S
E
E
L
S
G
G
R
L
K
P
K
Cat
Felis silvestris
Mouse
Mus musculus
Q99JY9
418
47339
S354
L
K
L
S
E
E
L
S
G
G
R
L
K
P
K
Rat
Rattus norvegicus
XP_342612
418
47616
S354
L
K
L
S
Q
E
L
S
G
G
R
I
K
P
K
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001513007
482
55165
S418
L
K
L
S
E
E
L
S
G
G
R
I
K
P
K
Chicken
Gallus gallus
Q90WD0
418
47403
S354
L
K
L
S
E
E
L
S
G
G
R
L
K
P
K
Frog
Xenopus laevis
P10995
377
41970
Y308
L
S
G
G
T
T
M
Y
P
G
I
A
D
R
M
Zebra Danio
Brachydanio rerio
NP_001003944
418
47376
S354
L
K
L
S
E
E
L
S
G
G
K
L
K
P
K
Tiger Blowfish
Takifugu rubipres
O73723
418
47447
S354
L
K
M
S
E
E
L
S
G
G
K
L
K
P
K
Fruit Fly
Dros. melanogaster
P32392
418
47014
S354
L
R
I
S
E
N
L
S
E
G
R
I
K
P
K
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Q9N4I0
425
48069
S361
L
Q
M
S
E
T
L
S
G
G
R
L
K
P
K
Sea Urchin
Strong. purpuratus
XP_780265
418
47124
S354
L
K
L
S
E
Q
L
S
G
G
K
L
K
P
K
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q9SAF1
427
47641
T363
V
L
A
N
N
A
R
T
G
G
E
I
T
S
Q
Baker's Yeast
Sacchar. cerevisiae
P47117
449
49523
L386
N
R
I
A
Q
S
E
L
L
S
G
T
K
S
T
Red Bread Mold
Neurospora crassa
P78712
439
47833
R373
R
I
K
A
S
E
V
R
S
G
G
A
K
S
G
Conservation
Percent
Protein Identity:
100
84.6
N.A.
73.6
N.A.
99.7
91.1
N.A.
78.2
98.5
37.3
97.3
96.6
80.6
N.A.
76
84.6
Protein Similarity:
100
91.8
N.A.
73.8
N.A.
100
96.4
N.A.
83.4
99.7
52.6
99.2
99.5
90.6
N.A.
85.1
92.5
P-Site Identity:
100
6.6
N.A.
100
N.A.
100
86.6
N.A.
93.3
100
13.3
93.3
86.6
66.6
N.A.
80
86.6
P-Site Similarity:
100
20
N.A.
100
N.A.
100
100
N.A.
100
100
20
100
100
86.6
N.A.
93.3
100
Percent
Protein Identity:
N.A.
N.A.
N.A.
58.7
59.2
61
Protein Similarity:
N.A.
N.A.
N.A.
74.9
69.2
72.4
P-Site Identity:
N.A.
N.A.
N.A.
13.3
6.6
20
P-Site Similarity:
N.A.
N.A.
N.A.
46.6
33.3
33.3
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
0
0
7
19
0
7
0
0
0
0
0
13
0
0
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
0
0
7
0
0
0
0
0
0
0
0
0
7
0
0
% D
% Glu:
0
0
0
0
63
57
7
0
7
7
13
0
0
0
0
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
7
7
0
0
0
0
69
88
13
0
0
7
13
% G
% His:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% H
% Ile:
0
7
13
0
0
0
0
0
0
0
7
25
0
0
0
% I
% Lys:
0
57
7
0
0
0
0
0
0
0
19
0
82
0
69
% K
% Leu:
75
7
50
0
0
7
69
13
7
0
0
57
0
0
0
% L
% Met:
0
0
13
0
0
0
7
0
0
0
0
0
0
0
7
% M
% Asn:
7
0
0
7
7
7
0
0
0
0
0
0
0
0
0
% N
% Pro:
0
0
0
0
0
0
0
0
7
0
0
0
0
69
0
% P
% Gln:
0
7
0
0
13
7
0
0
0
0
0
0
0
0
7
% Q
% Arg:
7
13
0
0
7
0
13
7
0
0
50
0
0
7
0
% R
% Ser:
0
7
0
69
7
7
0
69
13
7
0
0
7
19
0
% S
% Thr:
0
0
0
0
7
13
0
7
0
0
0
7
7
0
7
% T
% Val:
13
7
0
0
0
0
7
0
0
0
0
0
0
0
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
7
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _